Disease & Treatment
Paroxysmal Nocturnal Haemoglobinuria (PNH) is a very rare and debilitating disease of the bone marrow that affects the blood and major organs. It is a chronic, life-threatening illness and can have devastating effects upon a patient physically, mentally and emotionally.
A PNH diagnosis is confirmed by a specialized blood test called flow cytometry. Usually, several other tests are performed during the diagnostic process to rule out complications of PNH and assess its severity. These may include a bone marrow biopsy, blood tests, x-rays, CT scans…
There are several treatment options available to people living with PNH, depending on the progress and severity of the disease. The only cure for PNH is a bone marrow transplant; other treatments are supportive only but have significant benefits including a reduction…
New: Better Living with PNH
Choose Your Path and Live Your Life With PNH! A comprehensive guide with a holistic approach to better living with PNH. Find the most useful information and tools for you!
FIND A PNH SPECIALIST: View a list of board certified hematologists in your province
PLEASE NOTE: This information is intended for general knowledge only and is not to be substituted for medical advice and its accuracy is not guaranteed. Please consult with your medical practitioner for further information regarding your personal circumstances.
This information has been prepared by PNHSAA Inc., is copyright protected and is used with their permission.
- chronic severe fatigue
- abdominal pain
- muscular pain
- joint pain
- dark/unusually coloured urine
- lack of mental clarity
- forgetfulness, difficulty concentrating
- tingling or numbness, particularly in the extremities
- shortness of breath
- loss of appetite
- esophageal (gullet) pain
- erectile dysfunction
- arrhythmia (irregular heartbeat)
- difficulty dealing with daily tasks and situations
- digestive problems
- lack of motivation